Accommodations in Serra Mesa You’ll Love

Affordable, Top-Rated Places to Stay in Serra Mesa – For Every Budget

Looking for accommodation in Serra Mesa (California)? Discover a wide range of places to stay starting at just $28.65 per night – from hotels and bed & breakfasts to vacation rentals. Whether you're visiting for business or leisure, you'll find the perfect place that fits your budget and travel needs. Book your ideal Serra Mesa accommodation today!

We found 506 Accommodations in Serra Mesa and the surrounding area (within 20 miles)

Wyndham Garden San Diego

Hotel in San Diego near Serra Mesa, California , 3737 Sports Arena Boulevard

This 100% nonsmoking property is 6.5 mi from downtown San Diego and within 5 minutes drive of SeaWorld San Diego.

Parking
Restaurant
Family rooms

Good 2126 Reviews 7.1

from $97.19 Show details »

SureStay Hotel by Best Western San Diego...

Hotel in San Diego near Serra Mesa, California , 4545 Mission Bay Dr

Located less than 1 mi from Mission Bay Park & Public Golf Course, this nonsmoking California hotel features free WiFi and cable TV with HBO film chan...

Parking
Pets allowed
Family rooms
Outdoor pool
Kid-friendly buffet

Good 1300 Reviews 7.4

from $70.71 Show details »

Homewood Suites by Hilton San Diego Hote...

Hotel in San Diego near Serra Mesa, California , 2201 Hotel Circle South

Homewood Suites by Hilton San Diego Hotel Circle/SeaWorld Area is conveniently located off Interstate 8 in Hotel Circle.

Parking
Pets allowed
Fitness centre
Family rooms
Spa and wellness centre

Very good 671 Reviews 8.3

from $144.38 Show details »

The Little Italy Hotel Downtown San Dieg...

Hotel in San Diego near Serra Mesa, California , 1646 Front Street

Moments from San Diego's most popular attractions as well as the international airport, this hotel provides comfortable guestrooms and many modern con...

Parking
Restaurant
Pets allowed
Bar
Sauna

Very good 287 Reviews 8.5

from $107.39 Show details »

Hampton Inn San Diego Downtown

Hotel in San Diego near Serra Mesa, California , 1531 Pacific Highway

Directly off the I-5 motorway and 8 minutes' drive from San Diego International Airport.

Parking
Pets allowed
Fitness centre
Family rooms
Outdoor pool

Good 1734 Reviews 7.8

from $128.94 Show details »

Hampton Inn by Hilton San Diego - Kearny...

Hotel in San Diego near Serra Mesa, California , 5434 Kearny Mesa Road

In Kearny Mesa, 9 miles from downtown San Diego, this hotel offers an outdoor swimming pool and hot breakfast buffet.

Parking
Pets allowed
Fitness centre
Outdoor pool
Swimming pool

Fabulous 433 Reviews 8.6

from $114.39 Show details »

DoubleTree By Hilton San Diego Hotel Cir...

Hotel in San Diego near Serra Mesa, California , 1515 Hotel Circle South

Ideally situated just off I-8 and only a short drive from the downtown area attractions, this hotel features spacious and modern accommodations, compl...

Parking
Restaurant
Pets allowed
Bar
Fitness centre

Pleasant 599 Reviews 6.4

from $131.02 Show details »

Hilton San Diego Mission Valley

Hotel in San Diego near Serra Mesa, California , 901 Camino del Rio South

Centrally located in San Diego’s Mission Valley, Hilton San Diego Mission Valley offers an outdoor heated pool and a restaurant with a lounge on sit...

Parking
Restaurant
Bar
Fitness centre
Family rooms

Good 1768 Reviews 7.9

from $131.02 Show details »

DoubleTree by Hilton San Diego-Mission V...

Hotel in San Diego near Serra Mesa, California , 7450 Hazard Center Drive

DoubleTree by Hilton San Diego-Mission Valley offers an indoor and an outdoor pool with a hot tub bordered by tropical palms.

Parking
Restaurant
Pets allowed
Bar
Fitness centre

Very good 358 Reviews 8.0

from $126.31 Show details »

Holiday Inn Express San Diego Airport-Ol...

Hotel in San Diego near Serra Mesa, California , 1955 San Diego Avenue

Located 3 mi from San Diego International Airport, this hotel offers free shuttles to the airport, San Diego Amtrak Station and more.

Parking
Fitness centre
Outdoor pool
Swimming pool
Swimming Pool

Fabulous 654 Reviews 8.8

from $156.33 Show details »

Days Inn by Wyndham San Diego Hotel Circ...

Hotel in San Diego near Serra Mesa, California , 543 Hotel Circle South

Located 5 mi away from San Diego International Airport, Days Inn by Wyndham San Diego Hotel Circle Near SeaWorld offers spacious rooms equipped with f...

Parking
Restaurant
Pets allowed
Fitness centre
Family rooms

Good 4447 Reviews 7.8

from $97.25 Show details »

Porto Vista Hotel In Little Italy

Hotel in San Diego near Serra Mesa, California , 1835 Columbia Street

Located in Downtown San Diego’s Little Italy, Porto Vista Hotel In Little Italy offers a bar with panoramic views of San Diego Harbor and San Diego ...

Parking
Restaurant
Pets allowed
Bar
Fitness centre

Good 1216 Reviews 7.1

from $99.36 Show details »

The Atwood Hotel San Diego - SeaWorld/Zo...

Motel in San Diego near Serra Mesa, California , 1201 Hotel Circle South

San Diego International Airport is 10 minutes' drive from The Atwood Hotel San Diego - SeaWorld/Zoo, which offers an outdoor pool with cabanas and a 1...

Parking
Restaurant
Pets allowed
Bar
Family rooms

Good 2464 Reviews 7.8

from $79.20 Show details »

The Bristol Hotel San Diego

Hotel in San Diego near Serra Mesa, California , 1055 First Avenue

Adjacent to the Gaslamp Quarter and close to the Marina and Little Italy, The Bristol Hotel offers a Boutique experience in the heart of Downtown San ...

Parking
Fitness centre

Good 1071 Reviews 7.8

from $150.09 Show details »

Harborview Inn & Suites-Convention Cente...

Motel in San Diego near Serra Mesa, California , 550 West Grape Street

Located in the heart of San Diegos Little Italy, this hotel is than 2.5 mi from Petco Park, the Gaslamp District and the Convention Center.

Parking
Family rooms

Good 446 Reviews 7.2

from $73.52 Show details »

Paradise Point Resort & Spa

Resort in San Diego near Serra Mesa, California , 1404 Vacation Road

On a lush island in Mission Bay, this beautiful resort features a full-service spa and tropical gardens.

Parking
Restaurant
Pets allowed
Bar
Sauna

Very good 966 Reviews 8.3

from $187.98 Show details »

Handlery Hotel San Diego

Hotel in San Diego near Serra Mesa, California , 950 Hotel Circle North

Located just off I-8, this hotel and resort is just 10 minutes drive from downtown San Diego.

Parking
Restaurant
Pets allowed
Bar
Fitness centre

Good 2580 Reviews 7.8

from $87.29 Show details »

The US Grant, a Luxury Collection Hotel,...

Hotel in San Diego near Serra Mesa, California , 326 Broadway

Experience luxurious accommodations, exceptional service and unrivaled amenities in the heart of San Diego at this elegant historic hotel, located onl...

Parking
Restaurant
Pets allowed
Bar
Fitness centre

Very good 110 Reviews 8.1

from $285.47 Show details »

Hotel Iris - Mission Valley-San Diego Zo...

Hotel in San Diego near Serra Mesa, California , 625 Hotel Circle South

Located in Mission Valley, just minutes from several of San Diego's most exciting attractions, this hotel provides guests with convenient services and...

Parking
Pets allowed
Family rooms
Outdoor pool
Swimming pool

Disappointing 518 Reviews 4.7

from $69.77 Show details »

Howard Johnson by Wyndham San Diego Sea...

Hotel in San Diego near Serra Mesa, California , 3330 Rosecrans Street

Near the San Diego International Airport and the Marine Corps Recruit Depot, this hotel offers comfortable guestrooms.

Parking
Bar
Family rooms
Outdoor pool
Swimming pool

Pleasant 3506 Reviews 6.7

from $97.86 Show details »

Old Town Western Inn

Motel in San Diego near Serra Mesa, California , 3889 Arista Street

Off Interstate-5, this inn is 3 miles from Sea World theme park and the San Diego International Airport.

Parking
Family rooms

Very good 564 Reviews 8.0

from $86.23 Show details »

Mission View Inn & Suites San Diego Sea...

Hotel in San Diego near Serra Mesa, California , 641 Camino Del Rio South

Centrally located in Mission Valley, this hotel features an outdoor swimming pool and hot tub.

Parking
Fitness centre
Family rooms
Outdoor pool
Swimming pool

Okay 804 Reviews 5.6

from $79.14 Show details »

Sheraton Mission Valley San Diego Hotel

Hotel in San Diego near Serra Mesa, California , 1433 Camino Del Rio South

Close to attractions such as Qualcomm Stadium and the San Diego Zoo, this hotel in San Diego, California overlooks Mission Valley and offers enjoyable...

Parking
Restaurant
Pets allowed
Bar
Fitness centre

Good 580 Reviews 7.7

from $135.64 Show details »

Hotel Republic San Diego, Autograph Coll...

Hotel in San Diego near Serra Mesa, California , 421 West B Street

Located 11 minutes’ walk from Little Italy, Hotel Republic San Diego a Marriott Autograph Collection features a vibrant lounge, restaurant and conte...

Parking
Restaurant
Pets allowed
Bar
Fitness centre

Very good 327 Reviews 8.2

from $215.77 Show details »

The Sofia Hotel

Hotel in San Diego near Serra Mesa, California , 150 West Broadway

Located in downtown San Diego near the historic Gaslamp Quarter and Amtrak Station, this hotel offers relaxing spa services, contemporary guestrooms a...

Parking
Pets allowed
Fitness centre
Family rooms
Spa and wellness centre

Good 485 Reviews 7.8

from $106.37 Show details »

Number of Accommodations in Serra Mesa	506
Average price per night	$295.00
Lowest price per night	$28,65
Highest price per night	$5.124,14

Discover Serra Mesa – Your Guide to the Best Places to Stay

Planning a trip to Serra Mesa? Choosing the right place to stay is one of the most important parts of making your visit memorable. Whether you are looking for a luxury hotel, a cozy guesthouse, a modern apartment, or a family-friendly vacation rental, Serra Mesa offers a wide range of lodging options to suit every travel style and budget.

When deciding where to stay in Serra Mesa, consider key factors like location, amenities, reviews, and proximity to attractions or public transport. Do you prefer being in the heart of the city close to restaurants, shops, and nightlife? Or do you want a quiet neighborhood with a more local feel? With so many types of accommodations in Serra Mesa, from boutique hotels to spacious homes, you are sure to find something that fits your needs.

Tips for Finding the Perfect Stay in Serra Mesa

To find the perfect place to stay in Serra Mesa, consider your budget, preferred location, and the amenities you need. Do you want to stay in a hotel or a vacation rental or do your prefer an apartment or house with more space, privacy, and the opportunity to live like a local? Do you need access to a kitchen, laundry facilities, or a gym? Research online reviews and ratings to get an idea of what past guests have experienced. Also, consider the type of trip you're taking. If you're traveling with family, you may need a larger space or a kid-friendly environment. If you're on a romantic getaway, you may want a more intimate setting.

Check availability

Accommodations in Serra Mesa You’ll Love

Affordable, Top-Rated Places to Stay in Serra Mesa – For Every Budget

We found 506 Accommodations in Serra Mesa and the surrounding area (within 20 miles)

Discover Serra Mesa – Your Guide to the Best Places to Stay

Tips for Finding the Perfect Stay in Serra Mesa