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Holiday homes in La Mesa You’ll Love

Top-Rated La Mesa Holiday homes for Every Budget and Style!

Looking for a holiday home in La Mesa (California)? Browse a wide range of vacation rentals – from cozy retreats to spacious family homes – starting at just $50.00 per night. Whether you are planning a weekend getaway or a longer stay, you will find the perfect home away from home in the heart of La Mesa.

We found 105 Holiday-homes in La Mesa and the surrounding area (within 20 miles)

Family Retreat - basketball court & game room in La Mesa, USA

Family Retreat - basketball court & game...

Villa in La Mesa, California , 9131 Johnson Drive
Providing a garden, Family Retreat - basketball court & game room provides accommodations in La Mesa.
  • Parking
  • Pets allowed
  • Family rooms
  • Kids' outdoor play equipment

no reviews

from $92.00 Show details »

Luxe El Cajon Oasis with Pool, Fire Pit and Pavilion in El Cajon, USA

Luxe El Cajon Oasis with Pool, Fire Pit...

Villa in El Cajon near La Mesa, California
Luxe El Cajon Oasis with Pool, Fire Pit and Pavilion offers accommodations in El Cajon, 15 miles from San Diego Convention Center and 15 miles from Sa...
  • Parking
  • Spa and wellness centre
  • Outdoor pool
  • Swimming pool
  • Swimming Pool

Exceptional 1 Reviews 10.0

from $69.00 Show details »

Luxe Family Home in Bonita with Private Pool and Spa! in Bonita, USA

Luxe Family Home in Bonita with Private...

Holiday home in Bonita near La Mesa, California
Luxe Family Home in Bonita with Private Pool and Spa! is located in Bonita, just 11 miles from San Diego State University and 13 miles from San Diego ...
  • Parking
  • Pets allowed
  • Outdoor pool
  • Swimming Pool

Exceptional 3 Reviews 9.7

from $1.407.33 Show details »

Sweetwater by AvantStay Yard w Hottub Firepit in Bonita, USA

Sweetwater by AvantStay Yard w Hottub Fi...

Holiday home in Bonita near La Mesa, California
Sweetwater by AvantStay Yard w Hottub Firepit offers accommodations in Bonita, 11 miles from San Diego Convention Center and 11 miles from San Diego S...
  • Parking

no reviews

from $95.00 Show details »

Luxury Home with Views 15 Min to DT & Coronado Beach in San Diego, USA

Luxury Home with Views 15 Min to DT & Co...

Holiday home in San Diego near La Mesa, California , 7475 Timberwood Place
9.1 miles from San Diego Convention Center in San Diego, Luxury Home with Views 15 Min to DT & Coronado Beach provides accommodations with access to a...
  • Parking
  • Family rooms

Exceptional 3 Reviews 10.0

from $70.00 Show details »

Relaxing Retreat - 3 bdrm 2.5 bath house - sleeps up to 10! in San Diego, USA

Relaxing Retreat - 3 bdrm 2.5 bath house...

Holiday home in San Diego near La Mesa, California , 7642 Goode Street
Relaxing Retreat - 3 bdrm 2.5 bath house - sleeps up to 10! is located in San Diego, just 12 miles from San Diego Convention Center and 13 miles from ...
  • Parking
  • Pets allowed

no reviews

from $93.00 Show details »

Entire Modern 3-Bedroom Home, Ranch, Baby Crib, Gated Yard in San Diego, USA

Entire Modern 3-Bedroom Home, Ranch, Bab...

Holiday home in San Diego near La Mesa, California , 5831 Greycourt Ave
Entire Modern 3-Bedroom Home, Ranch, Baby Crib, Gated Yard offers accommodations in San Diego, 6.1 miles from San Diego Convention Center and 7.3 mile...
  • Parking
  • Pets allowed

Fabulous 31 Reviews 8.7

from $319.43 Show details »

Entire Private 4-Bedroom House w Garage, Big Yard, King Bed, Baby Crib in San Diego, USA

Entire Private 4-Bedroom House w Garage,...

Holiday home in San Diego near La Mesa, California , 6730 Bullock Dr
Entire Private 4-Bedroom House w Garage, Big Yard, King Bed, Baby Crib is located in San Diego, just 7.2 miles from San Diego Convention Center and 8....
  • Parking
  • Pets allowed

Disappointing 2 Reviews 4.5

from $82.00 Show details »

Elegant & Cozy 4-Bedroom Home with Pool, Spa, Views & Bonus Room! in San Diego, USA

Elegant & Cozy 4-Bedroom Home with Pool,...

Holiday home in San Diego near La Mesa, California , 8570 Parkbrook Ln
Elegant & Cozy 4-Bedroom Home with Pool, Spa, Views & Bonus Room! is located in San Diego, just 10 miles from San Diego Convention Center and 10 miles...
  • Parking
  • Pets allowed
  • Outdoor pool
  • Swimming Pool

Exceptional 1 Reviews 10.0

from $79.00 Show details »

Entire Modern 3-Bedroom Home w Gated Yard in San Diego, USA

Entire Modern 3-Bedroom Home w Gated Yar...

Holiday home in San Diego near La Mesa, California , 5551 Churchward Street
Featuring a garden, Entire Modern 3-Bedroom Home w Gated Yard provides accommodations in San Diego.
  • Parking
  • Pets allowed

no reviews

from $50.00 Show details »

Entire Private 3-Bedroom House w Gated Yard, Garage, Crib in San Diego, USA

Entire Private 3-Bedroom House w Gated Y...

Holiday home in San Diego near La Mesa, California , 9853 Saint George Street
Featuring a garden, Entire Private 3-Bedroom House w Gated Yard, Garage, Crib offers accommodations in San Diego.
  • Parking
  • Pets allowed

Exceptional 1 Reviews 10.0

from $395.04 Show details »

Spring Valley Family Home 13 Mi to San Diego! in Spring Valley, USA

Spring Valley Family Home 13 Mi to San D...

Holiday home in Spring Valley near La Mesa, California
Spring Valley Family Home 13 Mi to San Diego! offers accommodations in Spring Valley, 9.3 miles from San Diego State University and 13 miles from San ...
  • Parking
  • Pets allowed

no reviews

from $62.00 Show details »

Xlnc Exotic Home Sunnyside in San Diego, USA

Xlnc Exotic Home Sunnyside

Holiday home in San Diego near La Mesa, California , 660 Sunnyside Avenue
Xlnc Exotic Home Sunnyside is a recently renovated vacation home in San Diego where guests can make the most of the garden and shared lounge.
  • Parking
  • Pets allowed
  • Family rooms

Fabulous 3 Reviews 9.0

from $405.30 Show details »

Home away from Home in San Diego, USA

Home away from Home

Holiday home in San Diego near La Mesa, California , 905 60th Street
Home away from Home is located in San Diego, just 7.4 miles from San Diego Zoo and 7.5 miles from San Diego Convention Center.
  • Parking
  • Pets allowed

no reviews

from $71.00 Show details »

Charming 3BR Home by Rather Be Properties in San Diego, USA

Charming 3BR Home by Rather Be Propertie...

Holiday home in San Diego near La Mesa, California , 5416 Geneva Avenue
Charming 3BR Home by Rather Be Properties is located in San Diego, just 6 miles from San Diego Convention Center and 6 miles from San Diego – Santa ...
  • Pets allowed

no reviews

from $265.20 Show details »

Spring Valley Sky House with Patios and Epic Views! in Spring Valley, USA

Spring Valley Sky House with Patios and...

Holiday home in Spring Valley near La Mesa, California
Spring Valley Sky House with Patios and Epic Views! offers accommodations in Spring Valley, 10 miles from San Diego State University and 14 miles from...
  • Parking
  • Spa and wellness centre

no reviews

from $435.24 Show details »

Updated San Diego Home with Private Yard and Grill! in San Diego, USA

Updated San Diego Home with Private Yard...

Holiday home in San Diego near La Mesa, California
Updated San Diego Home with Private Yard and Grill! is located in San Diego, just 5.6 miles from San Diego Zoo and 5.6 miles from San Diego Convention...
  • Parking
  • Pets allowed
  • Spa and wellness centre

Very good 8 Reviews 8.3

from $273.98 Show details »

Sun-Soaked Home Less Than 9 Mi to Downtown San Diego in Lemon Grove, USA

Sun-Soaked Home Less Than 9 Mi to Downto...

Holiday home in Lemon Grove near La Mesa, California
Sun-Soaked Home Less Than 9 Mi to Downtown San Diego offers accommodations in Lemon Grove, 5.6 miles from San Diego State University and 9.2 miles fro...
  • Parking
  • Pets allowed

Exceptional 1 Reviews 10.0

from $298.67 Show details »

Cozy Home with Downtown View in San Diego, USA

Cozy Home with Downtown View

Holiday home in San Diego near La Mesa, California , 2554 55th Street
Offering a garden, Cozy Home with Downtown View features accommodations in San Diego.
  • Parking
  • Family rooms

Fabulous 40 Reviews 8.8

from $208.14 Show details »

Spacious Family Retreat in the heart of San Diego in San Diego, USA

Spacious Family Retreat in the heart of...

Holiday home in San Diego near La Mesa, California , 2605 Blackton Drive
Spacious Family Retreat in the heart of San Diego is located in San Diego, just 4 miles from San Diego State University and 6.4 miles from San Diego Z...
  • Parking
  • Family rooms

Good 10 Reviews 7.9

from $323.78 Show details »

Charming Spring Valley Retreat with Private Pool! in Spring Valley, USA

Charming Spring Valley Retreat with Priv...

Holiday home in Spring Valley near La Mesa, California
Charming Spring Valley Retreat with Private Pool! is located in Spring Valley, just 7.6 miles from San Diego State University and 13 miles from San Di...
  • Parking
  • Outdoor pool
  • Swimming pool
  • Swimming Pool

Pleasant 1 Reviews 6.0

from $452.29 Show details »

Mountain Majesty- Your Serene Escape Awaits! home in Lemon Grove, USA

Mountain Majesty- Your Serene Escape Awa...

Holiday home in Lemon Grove near La Mesa, California
Mountain Majesty- Your Serene Escape Awaits! home is located in Lemon Grove, just 11 miles from San Diego Convention Center and 11 miles from San Dieg...
  • Parking

no reviews

from $68.00 Show details »

Exotic home 2bed 1 bath adams street in Lemon Grove, USA

Exotic home 2bed 1 bath adams street

Holiday home in Lemon Grove near La Mesa, California , 8354 Adams Street Unit B
Exotic home 2bed 1 bath adams street offers accommodations in Lemon Grove, 10 miles from San Diego Zoo and 10 miles from San Diego Convention Center.
  • Parking
  • Pets allowed
  • Family rooms

Superb 5 Reviews 9.2

from $245.30 Show details »

SD Hideaway! in Spring Valley, USA

SD Hideaway!

Holiday home in Spring Valley near La Mesa, California , 10420 Loma Rancho Drive
SD Hideaway! offers accommodations in Spring Valley, 8.3 miles from San Diego State University and 14 miles from San Diego Zoo.
  • Parking
  • Pets allowed
  • Family rooms
  • Outdoor pool
  • Swimming Pool

no reviews

from $99.00 Show details »

Casa Küste - San Diegos Boho Gem in San Diego, USA

Casa Küste - San Diegos Boho Gem

Holiday home in San Diego near La Mesa, California , 3427 33rd Street
Casa Küste - San Diegos Boho Gem is a recently renovated vacation home in San Diego where guests can make the most of the garden and shared lounge.
  • Parking
  • Family rooms

Very good 1 Reviews 8.0

from $309.25 Show details »

Number of Holiday homes in La Mesa 105
Number of guest ratings 2,290
Average price per night $290.00
Lowest price per night $50,00
Highest price per night $2.360,67

Top 10 Cheapest Holiday-homes in La Mesa

Discover the Cheapest Holiday-homes in La Mesa – Ranked by Lowest Nightly Rates.

Top 10 Most Booked Holiday-homes in La Mesa

Check out the Most Booked Holiday-homes in La Mesa – Based on Guest Popularity.

Holiday homes in La Mesa (California), comfortable and familiar

Staying in a holiday or vacation home in La Mesa can be a great alternative to a hotel or resort. They can range from small cottages to luxurious villas, and are often located in popular tourist destinations such as beaches or mountains. One of the main benefits is the privacy and flexibility that comes with having your own space. Unlike a hotel room, a holiday home provides you with a living area, kitchen, and sometimes even outdoor space, allowing you to cook your own meals, relax in comfort, and enjoy the company of your friends or family without the interruptions of other guests.

Holiday homes often offer more space than a hotel room. This can be particularly useful for families or groups of friends traveling together, who may need more than one room or want to avoid the cramped feeling of a single hotel room. They can also provide a more authentic travel experience, allowing guests to immerse themselves in the local culture and lifestyle. This can be particularly appealing for those who prefer to stay in quieter, residential areas away from the hustle and bustle of tourist hotspots.

Find the best Holiday home in La Mesa for your needs

Holiday homes should offer a comfortable and enjoyable stay, providing all the necessary amenities and conveniences to make your vacation experience memorable. At a minimum, your holiday home in La Mesa should offer a clean and well-maintained living space with comfortable furnishings, adequate lighting, and climate control.

In addition to basic amenities such as a fully equipped kitchen, comfortable bedding, and clean linens and towels, holiday homes should also offer modern conveniences such as Wi-Fi, cable or streaming TV, and laundry facilities. A private outdoor space, such as a balcony or terrace, can also add to the overall enjoyment. They can also offer additional features such as a swimming pool, hot tub, or outdoor grill. Location is also important, for example, close to popular tourist attractions, restaurants and shopping areas.

Accommodation data and pictures provided by Booking.com