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Accommodations in Depew You’ll Love

Affordable, Top-Rated Places to Stay in Depew – For Every Budget

Looking for accommodation in Depew (Florida)? Discover a wide range of places to stay starting at just $52.00 per night – from hotels and bed & breakfasts to vacation rentals. Whether you're visiting for business or leisure, you'll find the perfect place that fits your budget and travel needs. Book your ideal Depew accommodation today!

We found 69 Accommodations in Depew and the surrounding area (within 20 miles)

Homewood Suites by Hilton Buffalo/Airport in Cheektowaga, USA

Homewood Suites by Hilton Buffalo/Airpor...

Hotel in Cheektowaga near Depew, Florida , 760 Dick Road
Located in Cheektowaga, 2.2 miles from Walden Galleria Mall, Homewood Suites by Hilton Buffalo/Airport provides accommodations with a fitness center, ...
  • Parking
  • Pets allowed
  • Fitness centre
  • Allergy-free room
  • Indoor pool

Very good 130 Reviews 8.2

from $144.06 Show details »

Hilton Garden Inn Buffalo Airport in Cheektowaga, USA

Hilton Garden Inn Buffalo Airport

Hotel in Cheektowaga near Depew, Florida , 4201 Genesee Street
Hilton Garden Inn Buffalo Airport features a fitness center, terrace, a restaurant and bar in Cheektowaga.
  • Parking
  • Restaurant
  • Pets allowed
  • Bar
  • Fitness centre

Fabulous 197 Reviews 8.8

from $148.31 Show details »

Hampton Inn Buffalo-Airport Galleria Mall in Cheektowaga, USA

Hampton Inn Buffalo-Airport Galleria Mal...

Hotel in Cheektowaga near Depew, Florida , 1745 Walden Avenue
Across from the Walden Galleria Mall shopping center and a short distance from Buffalo-Niagara International Airport, this hotel offers comfortable ac...
  • Pets allowed
  • Fitness centre
  • Family rooms
  • Allergy-free room
  • Indoor pool

Good 134 Reviews 7.9

from $117.56 Show details »

Comfort Inn & Suites Buffalo Airport in Buffalo, USA

Comfort Inn & Suites Buffalo Airport

Hotel in Buffalo near Depew, Florida , 4345 Genesee Street
Located off I-90, across the street from Buffalo-Niagara International Airport (BUF), Comfort Inn & Suites combines a convenient setting with a great ...
  • Pets allowed
  • Fitness centre
  • Indoor pool
  • Swimming pool
  • Swimming Pool

Good 637 Reviews 7.8

from $103.80 Show details »

M Hotel Buffalo in Cheektowaga, USA

M Hotel Buffalo

Hotel in Cheektowaga near Depew, Florida , 2040 Walden Avenue
Offering a restaurant, M Hotel Buffalo is located in Cheektowaga.
  • Parking
  • Restaurant
  • Pets allowed
  • Bar
  • Fitness centre

Pleasant 2352 Reviews 6.9

from $69.08 Show details »

Tru By Hilton Williamsville Buffalo Airport in Williamsville, USA

Tru By Hilton Williamsville Buffalo Airp...

Hotel in Williamsville near Depew, Florida , 48 Freeman Road Building B
Located in Williamsville, 5.8 miles from Walden Galleria Mall, Tru By Hilton Williamsville Buffalo Airport has accommodations with a shared lounge, fr...
  • Parking
  • Pets allowed
  • Bar
  • Fitness centre
  • Family rooms

Very good 217 Reviews 8.5

from $108.29 Show details »

Quality Inn Airport in Cheektowaga, USA

Quality Inn Airport

Inn in Cheektowaga near Depew, Florida , 4217 Genesee Street
This Quality Inn is located directly across the street from the Buffalo Airport, only 15 minutes from downtown.
  • Parking
  • Fitness centre

Poor 64 Reviews 3.5

from $86.44 Show details »

Extended Stay America Suites - Buffalo - Airport in Buffalo, USA

Extended Stay America Suites - Buffalo -...

Hotel in Buffalo near Depew, Florida , 901 Dick Road
This hotel is ideally located only minutes from Buffalo Niagara International Airport and motorway I-90, and features many complimentary amenities, in...
  • Parking
  • Pets allowed
  • Fitness centre
  • Family rooms
  • Indoor pool

Okay 191 Reviews 5.7

from $80.29 Show details »

Village Haven Inn & Extended Stay in Clarence, USA

Village Haven Inn & Extended Stay

Hotel in Clarence near Depew, Florida , 9370 Main Street
Featuring a garden, Village Haven Inn & Extended Stay is located in Clarence in the New York region, 9.2 miles from Walden Galleria Mall and 9.5 miles...
  • Parking
  • Pets allowed
  • Family rooms

Very poor 38 Reviews 2.5

from $58.50 Show details »

Red Roof Inn Buffalo - Niagara Airport in Williamsville, USA

Red Roof Inn Buffalo - Niagara Airport

Motel in Williamsville near Depew, Florida , 146 Maple Drive
Only 2.5 mi from Buffalo Niagara International Airport, this contemporary hotel is conveniently located off Interstate 90 with restaurant and shopping...
  • Parking
  • Pets allowed
  • Allergy-free room

Okay 287 Reviews 5.8

from $58.18 Show details »

Garden Place Hotel in Buffalo, USA

Garden Place Hotel

Hotel in Buffalo near Depew, Florida , 6615 Transit Road
Salvatores Garden Place Hotel in Williamsville, NY is in the center of everything, offering easy access to Diamond Hawk Golf Course, Burchfield Penny ...
  • Parking
  • Restaurant
  • Pets allowed
  • Bar
  • Sauna

Good 1386 Reviews 7.0

from $61.10 Show details »

Hampton Inn Buffalo-Williamsville in Williamsville, USA

Hampton Inn Buffalo-Williamsville

Hotel in Williamsville near Depew, Florida , 5455 Main Street
Located in Williamsville, within 4 miles of University of Buffalo and 4.2 miles of Walden Galleria Mall, Hampton Inn Buffalo-Williamsville provides ac...
  • Parking
  • Pets allowed
  • Fitness centre
  • Indoor pool
  • Swimming Pool

Fabulous 172 Reviews 8.8

from $147.12 Show details »

Holiday Inn Express & Suites Buffalo Airport by IHG in Cheektowaga, USA

Holiday Inn Express & Suites Buffalo Air...

Hotel in Cheektowaga near Depew, Florida , 131 Buell Avenue
Holiday Inn Express & Suites Buffalo Airport by IHG is located in Cheektowaga, 2.6 miles from Walden Galleria Mall and 6.4 miles from University of Bu...
  • Parking
  • Pets allowed
  • Fitness centre
  • Indoor pool
  • Swimming pool

Good 398 Reviews 7.4

from $90.09 Show details »

Buffalo Airport Hotel in Cheektowaga, USA

Buffalo Airport Hotel

Hotel in Cheektowaga near Depew, Florida , 4600 Genesee Street
"Buffalo Airport's only Full Service Hotel" Adjacent to Buffalo International Airport, this Cheektowaga hotel offers free 24-hour airport shuttles, a...
  • Parking
  • Restaurant
  • Bar
  • Fitness centre
  • Family rooms

Good 335 Reviews 7.4

from $59.67 Show details »

Hawthorn Suites by Wyndham Williamsville Buffalo Airport in Williamsville, USA

Hawthorn Suites by Wyndham Williamsville...

Hotel in Williamsville near Depew, Florida , 8005 Sheridan Dr
Located within 7.3 miles of Walden Galleria Mall and 7.5 miles of University of Buffalo, Hawthorn Suites by Wyndham Williamsville Buffalo Airport prov...
  • Parking
  • Pets allowed
  • Fitness centre
  • Family rooms
  • Indoor pool

Pleasant 252 Reviews 6.5

from $94.75 Show details »

Residence Inn by Marriott Buffalo Galleria Mall in Cheektowaga, USA

Residence Inn by Marriott Buffalo Galler...

Hotel in Cheektowaga near Depew, Florida , 107 Anderson Road
Located in Cheektowaga and with Walden Galleria Mall reachable within a 16-minute walk, Residence Inn by Marriott Buffalo Galleria Mall has express ch...
  • Parking
  • Pets allowed
  • Fitness centre
  • Family rooms
  • Swimming pool

Very good 100 Reviews 8.1

from $142.30 Show details »

FairBridge Inn Express Buffalo Airport Williamsville in Williamsville, USA

FairBridge Inn Express Buffalo Airport W...

Motel in Williamsville near Depew, Florida , 7200 Transit Road
FairBridge Inn Express Buffalo Airport Williamsville is 3.5 mi from Buffalo-Niagara International Airport.
  • Parking
  • Family rooms

Poor 413 Reviews 3.9

from $54.19 Show details »

La Quinta Inn by Wyndham Buffalo Airport in Williamsville, USA

La Quinta Inn by Wyndham Buffalo Airport

Hotel in Williamsville near Depew, Florida , 6619 Transit Road
La Quinta Inn by Wyndham Buffalo Airport is located in Williamsville, 5.1 miles from Walden Galleria Mall and 7.7 miles from University of Buffalo.
  • Pets allowed
  • Fitness centre

Good 350 Reviews 7.6

from $79.28 Show details »

Fairfield Inn & Suites – Buffalo Airport in Cheektowaga, USA

Fairfield Inn & Suites – Buffalo Airport

Hotel in Cheektowaga near Depew, Florida , 4271 Genesee Street
Located 3 miles from Walden Galleria Mall, Fairfield Inn & Suites – Buffalo Airport offers 3-star accommodations in Cheektowaga and has free bikes, ...
  • Parking
  • Pets allowed
  • Fitness centre
  • Family rooms
  • Indoor pool

Very good 214 Reviews 8.2

from $119.89 Show details »

Best Western Galleria Inn & Suites in Cheektowaga, USA

Best Western Galleria Inn & Suites

Hotel in Cheektowaga near Depew, Florida , 601 Dingens Street
Buffalo Niagara International Airport is 8 mi away from this New York hotel.
  • Parking
  • Fitness centre
  • Family rooms
  • Outdoor pool
  • Swimming pool

Pleasant 396 Reviews 6.9

from $88.24 Show details »

Courtyard by Marriott Buffalo Airport in Cheektowaga, USA

Courtyard by Marriott Buffalo Airport

Hotel in Cheektowaga near Depew, Florida , 4243 Genesee Street
Located in Cheektowaga, Courtyard by Marriott Buffalo Airport offers 3-star accommodations with a shared lounge and a bar.
  • Parking
  • Restaurant
  • Pets allowed
  • Bar
  • Fitness centre

Fabulous 204 Reviews 8.6

from $144.06 Show details »

Reikart House Buffalo, a Tribute Portfolio Hotel in Amherst, USA

Reikart House Buffalo, a Tribute Portfol...

Hotel in Amherst near Depew, Florida , 5000 Main Street
Reikart House Buffalo, a Tribute Portfolio Hotel has free bikes, fitness center, a restaurant and bar in Amherst.
  • Parking
  • Restaurant
  • Pets allowed
  • Bar
  • Fitness centre

Exceptional 50 Reviews 9.5

from $374.24 Show details »

Motel 6-Buffalo, NY - Airport - Williamsville in Williamsville, USA

Motel 6-Buffalo, NY - Airport - Williams...

Hotel in Williamsville near Depew, Florida , 52 Freeman Road
Located close to Interstate 90, this motel offers Wi-Fi, an outdoor pool, and rooms that feature a seating area and work desk.
  • Parking
  • Pets allowed
  • Outdoor pool
  • Swimming pool
  • Swimming Pool

Passable 388 Reviews 5.0

from $48.52 Show details »

Best Western Buffalo Inn & Suites in Buffalo, USA

Best Western Buffalo Inn & Suites

Hotel in Buffalo near Depew, Florida , 50 Freeman Rd
The Eva Hotel Buffalo Airport, BW Signature Collection is located off Interstate 90 and has a transfer service available to the Buffalo Niagara Intern...
  • Parking

Very good 841 Reviews 8.1

from $99.10 Show details »

Clarence Inn Extended Stay in Clarence Center, USA

Clarence Inn Extended Stay

Hotel in Clarence Center near Depew, Florida , 9079 Main Street
Located in Clarence Center, 8.6 miles from Walden Galleria Mall, Clarence Inn Extended Stay has accommodations with free WiFi and free private parking...
  • Parking

Very good 89 Reviews 8.3

from $99.46 Show details »

Number of Accommodations in Depew 69
Average price per night $157.00
Lowest price per night $52,00
Highest price per night $495,02

Discover Depew – Your Guide to the Best Places to Stay

Planning a trip to Depew? Choosing the right place to stay is one of the most important parts of making your visit memorable. Whether you are looking for a luxury hotel, a cozy guesthouse, a modern apartment, or a family-friendly vacation rental, Depew offers a wide range of lodging options to suit every travel style and budget.

When deciding where to stay in Depew, consider key factors like location, amenities, reviews, and proximity to attractions or public transport. Do you prefer being in the heart of the city close to restaurants, shops, and nightlife? Or do you want a quiet neighborhood with a more local feel? With so many types of accommodations in Depew, from boutique hotels to spacious homes, you are sure to find something that fits your needs.

Tips for Finding the Perfect Stay in Depew

To find the perfect place to stay in Depew, consider your budget, preferred location, and the amenities you need. Do you want to stay in a hotel or a vacation rental or do your prefer an apartment or house with more space, privacy, and the opportunity to live like a local? Do you need access to a kitchen, laundry facilities, or a gym? Research online reviews and ratings to get an idea of what past guests have experienced. Also, consider the type of trip you're taking. If you're traveling with family, you may need a larger space or a kid-friendly environment. If you're on a romantic getaway, you may want a more intimate setting.

Accommodation data and pictures provided by Booking.com